Ludlum D.B., 1988: Phosphotriester formation by the haloethylnitrosoureas and repair of these lesions by escherichia coli bs21 extracts. Nucleic Acids Research: 5661-5672 The alkylation of phosphatase in Dna by therapeutically active haloethylnitrosoureas was studied by reacting N-chloroethyl-N-nitrosourea (Cnu) with dTpdT, separating the products by Hplc, and identifying them by co-chromatography with authentic markers. Both hydroxyethyl […]
↧