Creighton T.E., 1979: Intermediates in the re folding of reduced rnase a. Journal Of Molecular Biology: 411-432 The intermediates with 1, 2, 3 or 4 disulfide bonds which accumulate during unfolding of native RNase and refolding of the reduced protein were trapped by rapid alkylation with iodoacetate and separated by ion-exchange chromatography. They were characterized […]
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