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Interindividual and intraindividual variability in labetalol pharmacokinetics

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“Matzke G.R., 1988: Interindividual and intraindividual variability in labetalol pharmacokinetics. Journal Of Clinical Pharmacology: 344-349 The between-subject and within-subject variability in the pharmacokinetics of labetalol at steady state were determined. Sixteen nonobese normal volunteers (mean age, 27 years) received five different formulations of labetalol orally on five different occasions every 12 hours for five doses. […]

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